Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease: a meta-analysis and systematic review.
- 2025-09-12
- Systematic Review · n = 1,970
- Frontiers in pharmacology 16
- Shuyu Zheng
- Meng Zhang
- Wenkuan Wang
- Qian Zhang
- Ning Zhang
- PubMed: 41019991
- DOI: 10.3389/fphar.2025.1556368
- High evidence
- Clinical
SM preparations led to reductions in serum creatinine (Scr), blood urea nitrogen (BUN), urinary albumin excretion rate (UAER), 24-h urinary total protein (24 h-utp), C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and endothelin-1 (ET-1) levels among patients with DKD (P < 0.05).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes