Rehmannia and Improved Kupperman Index

• Rehmannia glutinosa for perimenopausal syndrome in patients with breast cancer: A systematic review and meta-analysis.

  • 2025-07
  • Meta-Analysis · n = 139
  • Saudi medical journal 46(7)
  • • Dejia Kong
    • Feixiang Huang
    • Wenhua Liu
    • Ma Lin
    • Zhumei Sheng
    • Junmiao Xu

  • PubMed: 40628433
  • DOI: 10.15537/smj.2025.46.7.20240572

  7 Insights on

  • Improved Kupperman Index

  • High evidence
  • Clinical

  CHM with Rehmannia glutinosa as the monarch drug significantly improved the Kupperman index (MD= -12.79, p<0.01)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes