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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Reishi and Reduced Heart Rate

Doses used in studies

mg/day: 200–11,200 (median 3,350, IQR 400–8,650) — 2 studies

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Efficacy of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Supplementation on Psychological Stress and Selective Fitness Profile Parameters in Female College Students in West Bengal, India.
- 2024-01-01
- RCT · n = 78
- International journal of medicinal mushrooms 26(11)
- - Sudeep Mitra
  - Mousumi Mitra
  - Dilip Kumar Nandi
  - Mantu Saha
  - Amit Bandyopadhyay
- PubMed: 39241163
- DOI: 10.1615/intjmedmushrooms.2024055300
8 Insights on
- Reduced Heart Rate
- High evidence
- Adults
Significant differences in the post-experimental GL1000mg group for heart rate (HR) ... compared with the placebo group.
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
1000 mg/day
The Nutritional Significance of Ganoderma lucidum on Human Health: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials.
- 2025-06-12
- Review · n = 971
- Food science & nutrition 13(6)
- - Ali Jafari
  - Helia Mardani
  - Zahra Mirzaei Fashtali
  - Bahareh Arghavan
- PubMed: 40510787
- DOI: 10.1002/fsn3.70423
17 Insights on
- Reduced Heart Rate
- High evidence
- Clinical
heart rate (HR) (WMD = -3.92; 95% CI: -7.45, -0.40; p = 0.029)
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
200-11,200 mg/day