Effect of saffron extract supplementation on mood in healthy adults with subclinical symptoms of depression: a randomized, double-blind placebo-controlled study.
- 2025-12
- RCT
- The American journal of clinical nutrition 122(6)
- Camille Amadieu
- Quentin Leyrolle
- Milena Farneti
- Andrea Anesi
- Eva Bruchet
- Juliette Montet
- Sandra Dexpert
- David Gaudout
- Fulvio Mattivi
- Line Pourtau
- Nathalie Castanon
- Lucile Capuron
- PubMed: 41047129
- DOI: 10.1016/j.ajcnut.2025.09.050
- High evidence
- Clinical
There were no significant effects on inflammatory parameters or hypothalamic-pituitary-adrenal axis reactivity.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No