The effect of saffron supplementation on indices of oxidative stress, inflammation, mental health, and quality of life in patients with Parkinson's disease: a randomized, triple-blind, placebo-controlled clinical trial.
- 2026
- RCT · n = 92
- Food & function 17(2)
- Zahra Hajhashemy
- Mohammad Bagherniya
- Omid Sadeghi
- Fariborz Khorvash
- Gholamreza Askari
- PubMed: 41439298
- DOI: 10.1039/d5fo01924a
- High evidence
- Rigorous Journal
- Clinical
significant favorable effects of saffron on C-reactive protein (CRP) values (adjusted mean difference: -3.84 mg L⁻¹ and 95% CI: -5.61, -2.08; P_ANCOVA < 0.001)
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 100 mg/day