Saw Palmetto and Improved Chronic Prostatitis Symptom Index Score

Doses used in studies

mg/day: 320 (median 320, IQR 320–320) — 1 study

Time to effect

Median: 7.5 weeks · IQR 5.3 weeks–9.8 weeks · Range 3 weeks–2.8 months — Reported in 2 of 2 studies

Safety in these studies

Overall tolerabilityReported
Only minor adverse events were observed across the entire study population.
from: The efficacy and safety of Serenoa repens extract for the treatment of patients with chron

2 of 2 papers

The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial.
- 2021-01-16
- RCT · n = 226
- World journal of urology 39(9)
- - Kai Zhang
  - Run-Qi Guo
  - Shan-Wen Chen
  - Bin Chen
  - Xin-Bo Xue
  - Shan Chen
  - Jian Huang
  - Ming Liu
  - Ye Tian
  - Li Zuo
  - Ming Chen
  - Li-Qun Zhou
- PubMed: 33452912
- DOI: 10.1007/s00345-020-03577-2
5 Insights on
- Improved Chronic Prostatitis Symptom Index Score
- High evidence
- Large Human Trial
- Clinical
Compared to the placebo, SRE led to statistically significant improvements in the NIH-CPSI total score and sub-scores.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Chronic bacterial prostatitis: efficacy of short-lasting antibiotic therapy with prulifloxacin (Unidrox®) in association with saw palmetto extract, lactobacillus sporogens and arbutin (Lactorepens®).
- 2014-07-19
- RCT · n = 210
- BMC urology 14
- - Gian Maria Busetto
  - Riccardo Giovannone
  - Matteo Ferro
  - Stefano Tricarico
  - Francesco Del Giudice
  - Deliu Victor Matei
  - Ottavio De Cobelli
  - Vincenzo Gentile
  - Ettore De Berardinis
- PubMed: 25038794
- DOI: 10.1186/1471-2490-14-53
6 Insights on
- Improved Chronic Prostatitis Symptom Index Score
- High evidence
- Large Human Trial
- Clinical
A statistically significant difference was found at the time of the follow-up between Group A and B in the NIH-CPSI questionnaire score, symptoms evidence and serum PSA.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
320 mg

Saw Palmetto and Improved Chronic Prostatitis Symptom Index Score

The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial.

Chronic bacterial prostatitis: efficacy of short-lasting antibiotic therapy with prulifloxacin (Unidrox®) in association with saw palmetto extract, lactobacillus sporogens and arbutin (Lactorepens®).