Saw Palmetto and Improved Erectile Function

Doses used in studies

mg/day: 320 (median 320, IQR 320–320) — 1 study

Time to effect

Median: 4.2 months · IQR 3.5 months–4.9 months · Range 2.8 months–5.6 months — Reported in 2 of 2 studies

Safety in these studies

Overall tolerabilityReported
The Serenoa repens extract was effective, safe, well-tolerated, and clinically and statistically superior to placebo in the target LUTS/BPH population.
from: Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperpl
Overall tolerabilityReported
Only minor adverse events were observed across the entire study population.
from: The efficacy and safety of Serenoa repens extract for the treatment of patients with chron
adverse eventsReported2 (1.18%) of 169 patients in the placebo group and 3 (1.89) of 159 patients in the Serenoa repens extract group experienced 1 or more adverse events
Two (1.18%) of 169 patients in the placebo group and 3 (1.89) of 159 patients in the Serenoa repens extract group experienced 1 or more adverse events.
from: Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperpl

2 of 2 papers

The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial.
- 2021-01-16
- RCT · n = 226
- World journal of urology 39(9)
- - Kai Zhang
  - Run-Qi Guo
  - Shan-Wen Chen
  - Bin Chen
  - Xin-Bo Xue
  - Shan Chen
  - Jian Huang
  - Ming Liu
  - Ye Tian
  - Li Zuo
  - Ming Chen
  - Li-Qun Zhou
- PubMed: 33452912
- DOI: 10.1007/s00345-020-03577-2
5 Insights on
- Improved Erectile Function
- High evidence
- Large Human Trial
- Clinical
Secondary efficacy endpoints included improvements within each domain of NIH-CPSI, clinical response rate, and International Index of Erectile Function 5 items (IIEF-5).
Effect
Neutral
Effect size
Small
Significant
No
Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial.
- 2019-03-14
- RCT · n = 354
- Urology 129
- - Zhangqun Ye
  - Jian Huang
  - Liqun Zhou
  - Shan Chen
  - Zengjun Wang
  - Lulin Ma
  - Dongfang Wang
  - Gongxian Wang
  - Shusheng Wang
  - Chaozhao Liang
  - Shaopeng Qiu
  - Xiaojian Gu
  - Jianhe Liu
  - Zhiliang Weng
  - Changli Wu
  - Qiang Wei
  - Liping Xie
  - Weizhen Wu
  - Yue Cheng
  - Jingqian Hu
  - Zhixian Wang
  - Xiaoyong Zeng
- PubMed: 30880074
- DOI: 10.1016/j.urology.2019.02.030
10 Insights on
- Improved Erectile Function
- High evidence
- Large Human Trial
- Clinical
Statistically significant improvement in the ... International Index of Erectile Function score were observed in the Serenoa repens extract group compared with those in the placebo group (P <.05).
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
320 mg

Saw Palmetto and Improved Erectile Function

The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial.

Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial.