Efficacy of Serenoa repens Extract Combined With Alfuzosin Versus Alfuzosin Alone in Men With Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: A Multicenter Randomized Study.
- 2025-10-16
- RCT
- The Prostate 86(2)
- Giulio Bevilacqua
- Dalila Carino
- Stefano Salciccia
- Alessandro Gentilucci
- Flavio Forte
- Massimiliano Di Marco
- Antonio Pastore
- Marco Martini
- Stefano Signore
- Alessandro Calarco
- Martino Recchia
- Olivia Voglino
- Valenzi Fabio Maria
- Pietro Viscuso
- Fabrizio Presicce
- Ervin Shehu
- Marco Frisenda
- Alessandro Sciarra
- PubMed: 41098072
- DOI: 10.1002/pros.70071
- High evidence
- Clinical
Nocturia improved significantly over time (p < 0.0001); the combination group showed greater benefit from Month 3 onward (p = 0.006).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- 320 mg/day