Saw Palmetto and Reduced Urinary Frequency

Doses used in studies

mg/day: 320 (median 320, IQR 320–320) — 1 study

Time to effect

Median: 4.3 months · IQR 3.7 months–5 months · Range 3 months–5.6 months — Reported in 2 of 2 studies

Safety in these studies

Overall tolerabilityReported
The Serenoa repens extract was effective, safe, well-tolerated, and clinically and statistically superior to placebo in the target LUTS/BPH population.
from: Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperpl
Overall tolerabilityReported
The herbal preparation (ProstateEZE Max) was shown to be well tolerated
from: A phase II randomised double-blind placebo-controlled clinical trial investigating the eff
adverse eventsReported2 (1.18%) of 169 patients in the placebo group and 3 (1.89) of 159 patients in the Serenoa repens extract group experienced 1 or more adverse events
Two (1.18%) of 169 patients in the placebo group and 3 (1.89) of 159 patients in the Serenoa repens extract group experienced 1 or more adverse events.
from: Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperpl

2 of 2 papers

Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial.
- 2019-03-14
- RCT · n = 354
- Urology 129
- - Zhangqun Ye
  - Jian Huang
  - Liqun Zhou
  - Shan Chen
  - Zengjun Wang
  - Lulin Ma
  - Dongfang Wang
  - Gongxian Wang
  - Shusheng Wang
  - Chaozhao Liang
  - Shaopeng Qiu
  - Xiaojian Gu
  - Jianhe Liu
  - Zhiliang Weng
  - Changli Wu
  - Qiang Wei
  - Liping Xie
  - Weizhen Wu
  - Yue Cheng
  - Jingqian Hu
  - Zhixian Wang
  - Xiaoyong Zeng
- PubMed: 30880074
- DOI: 10.1016/j.urology.2019.02.030
10 Insights on
- Reduced Urinary Frequency
- High evidence
- Large Human Trial
- Clinical
Secondary efficacy parameters included improvement of ... urinary frequency, and total prostate-specific antigen level.
Effect
Neutral
Effect size
Small
Significant
No
Dose
320 mg
A phase II randomised double-blind placebo-controlled clinical trial investigating the efficacy and safety of ProstateEZE Max: a herbal medicine preparation for the management of symptoms of benign prostatic hypertrophy.
- 2013-02-23
- RCT · n = 32
- Complementary therapies in medicine 21(3)
- - Samantha Coulson
  - Amanda Rao
  - Shoshannah L Beck
  - Elizabeth Steels
  - Helen Gramotnev
  - Luis Vitetta
- PubMed: 23642948
- DOI: 10.1016/j.ctim.2013.01.007
3 Insights on
- Reduced Urinary Frequency
- High evidence
- Clinical
The day-time urinary frequency in the active group also showed a significant reduction over the 3-months intervention (7.0-5.9 times per day, a reduction of 15.6% compared to no significant reduction change for the placebo group (6.2-6.3 times per day) (p < 0.03).
Effect
Beneficial
Effect size
Small
Significant
Yes

Saw Palmetto and Reduced Urinary Frequency

Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial.

A phase II randomised double-blind placebo-controlled clinical trial investigating the efficacy and safety of ProstateEZE Max: a herbal medicine preparation for the management of symptoms of benign prostatic hypertrophy.