Senna and Improved User Preference

• Sennosides vs magnesium hydroxide vs polyethylene glycol as a treatment for constipation in anorectal malformation: a randomized crossover trial.

  • 2025-08-26
  • RCT
  • Pediatric surgery international 41(1)
  • • Butsarin Nate-Anong
    • Jiraporn Khorana
    • Sireekarn Chantakhow
    • Jesda Singhavejsakul
    • Kanokkan Tepmalai

  • PubMed: 40856829
  • DOI: 10.1007/s00383-025-06174-9

  3 Insights on

  • Improved User Preference

  • High evidence
  • Clinical

  User preference scores favored Sennosides (7.00 ± 2.36) over Mg(OH)2 (6.33 ± 2.94) and PEG (5.06 ± 2.28) with p = 0.582.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No