Sesame and Reduced Phlebitis Incidence

• Effect of sesame oil and Nigella sativa oil on the prevention of amiodarone-induced phlebitis: a randomized controlled trial.

  • 2026-03-18
  • RCT · n = 108
  • Explore (New York, N.Y.) 22(3)
  • • Burcu Nal
    • Dilek Sari
    • Mehmet Ali Astarcioğlu
    • İsmail Şen

  • PubMed: 41880716
  • DOI: 10.1016/j.explore.2026.103403

  2 Insights on

  • Reduced Phlebitis Incidence

  • High evidence
  • Large Human Trial
  • Clinical

  Phlebitis was observed in 25% of patients in the sesame oil group, 33.3% in the Nigella sativa oil group, and 80.6% in the control group.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  five drops topically to a 10-cm area around the catheter site every 6 hours