Sophora and Improved Performance Status

• Meta-analysis of the effect of sophora flavescens on tumor metastasis-induced bone neuropathic pain.

  • 2024-11-19
  • Systematic Review · n = 463
  • Frontiers in pharmacology 15
  • • Cheng Chang
    • Di Sun
    • Zhilei Zhang
    • Lei He
    • Qiang Wang
    • Yingchao Shen
    • Hengzhou Zhu
    • Donghua Fan

  • PubMed: 39629083
  • DOI: 10.3389/fphar.2024.1474982

  2 Insights on

  • Improved Performance Status

  • High evidence
  • Clinical

  Specifically, the Karnofsky Performance Status (KPS) increase rate showed a combined risk ratio of 1.62 (95% CI: 1.32, 1.99, P < 0.0001), indicating improved performance status with treatment.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes