Effects of Spirulina platensis supplementation on quality of life, severity of disease and serum total antioxidant capacity, malondialdehyde and zonulin in constipation-predominant irritable bowel syndrome: protocol for a randomised, double-blinded, placebo-controlled clinical trial from Iran.
- 2025-04
- RCT
- BMJ open 15(4)
- Saeede Jafari Nasab
- Parisa Hajihashemi
- Awat Feizi
- Hassan Shahoon
- Alireza Ani
- Hamidreza Roohafza
- Peyman Adibi
- Mohammdanhasan Entezari
- Mohammad Bagherniya
- PubMed: 40262961
- DOI: 10.1136/bmjopen-2024-086521
- High evidence
- Clinical
secondary outcomes are the changes in the... serum malondialdehyde from baseline to the end of intervention
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 500 mg twice daily