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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Tribulus and Increased Testosterone Level

Research synthesisModerate evidenceSmall effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported beneficial effects of Tribulus supplementation on testosterone levels, with predominantly small effect sizes. The evidence is strongest in clinical populations (hypogonadal men and women with sexual dysfunction) at doses ranging from 400 to 770 mg/day, with effects typically observed at 6–12 weeks. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed).

  • Effective dose range: 400-770 mg/day
  • Studied populations: hypogonadal men, premenopausal and postmenopausal women with sexual dysfunction

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Most studies were conducted in clinical populations (hypogonadism or sexual dysfunction); effects may not generalize to healthy individuals or athletes.

Generated Jul 12, 2026
Doses used in studies
  • mg/day: 94–770 (median 575, IQR 247–760) — 3 studies
Time to effect
Median: 9.4 weeks · IQR 7.7 weeks–11.1 weeks · Range 6 weeks–3 months — Reported in 2 of 4 studies
Safety in these studies
4 of 4 papers
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