Turmeric and Improved ACR20 Response

• Curcumin for the clinical treatment of rheumatoid arthritis: a systematic review and meta-analysis of placebo-controlled randomized clinical trials.

  • 2026-01-12
  • Meta-Analysis · n = 244
  • Frontiers in immunology 16
  • • Yihua Fan
    • Zhiqiang Yi
    • Shijie Mao
    • Jialu Wen
    • Jiwei Zhang
    • Qiang Zhang
    • Ruihan Liu

  • PubMed: 41601662
  • DOI: 10.3389/fimmu.2025.1726157

  8 Insights on

  • Improved ACR20 Response

  • High evidence
  • Clinical

  curcumin significantly improved the following outcomes: American College of Rheumatology (ACR) 20 response (SMD = 4.35, 95%CI(2.22, 6.47), P < 0.0001; evidence certainty: very low)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes