Across 4 studies, all 4 reported statistically significant beneficial effects of turmeric on quality of life, with effect sizes ranging from small to large. The median study duration was 84 days (12 weeks), and effects were observed in clinical populations including people with functional dyspepsia, chronic lower back pain, and cancer. The most-studied dose was approximately 1 g/day of curcuminoids (often with piperine) in a limited number of studies.
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Effect sizes varied substantially across studies (small to large), and the largest study (n=4477) showed only a small effect, raising questions about clinical significance.
There is probably little to no difference in the rate of adverse events between this intervention and placebo (RR 1.26, 95% CI 0.51 to 3.08; 1 study, 89 participants; moderate CoE).
from: Non-Chinese herbal medicines for functional dyspepsia.Almost all the studies reported little to no difference in the rate of adverse events compared to placebo
from: Non-Chinese herbal medicines for functional dyspepsia.better tolerance to chemotherapy, fewer adverse effects
from: Efficacy and Safety of Curcumin as an Adjuvant to Standard Chemotherapy in Advanced and MeThe use of CHM and curcumin concomitant with standard therapy was associated with survival and quality-of-life benefits.
from: Unconventional Treatments for Pancreatic Cancer: A Systematic Review.better tolerance to chemotherapy, fewer adverse effects
from: Efficacy and Safety of Curcumin as an Adjuvant to Standard Chemotherapy in Advanced and MeThe intervention probably improves the quality of life, measured on the EQ-5D (MD 0.05, 95% CI 0.01 to 0.09)
Critical QoL scores greatly improved in the CL20192 group.
Curcumin-treated women displayed higher physical performance, better prognosis and QoL, better tolerance to chemotherapy, fewer adverse effects, and better PFS.
Among these, the use of CHM and curcumin concomitant with standard therapy was associated with survival and quality-of-life benefits.