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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Turmeric and Reduced C-Reactive Protein Levels

Research synthesisModerate evidenceModerate effect5 studies · 4 beneficial · 1 neutral · 0 harmful

Across 5 studies, 4 reported beneficial effects of turmeric (curcumin) on reducing C-reactive protein levels, with effect sizes predominantly moderate. The evidence is drawn largely from meta-analyses in clinical populations (rheumatoid arthritis, type 2 diabetes, metabolic syndrome) and one null trial in athletes. Median study duration was 42 days (from one study), and the only reported dose was 2 g/day.

  • Studied populations: clinical populations (rheumatoid arthritis, type 2 diabetes, metabolic syndrome)

Caveats: The majority of studies are meta-analyses of randomized trials, but one meta-analysis is rated very low quality and reports an unusually large effect (SMD = −2.91). The only null trial was in a small sample of athletes (n = 15), suggesting the effect may be less consistent in athletic populations. Doses and forms were poorly reported across studies, limiting dose-specific recommendations.

Generated Jul 12, 2026
Doses used in studies
  • g/day: 2 (median 2, IQR 22) 1 study
Time to effect
Median: 6 weeks · IQR 6 weeks6 weeks · Range 6 weeks6 weeks — Reported in 1 of 5 studies
Safety in these studies
5 of 5 papers
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