Curcuma longa improves endothelial glycocalyx integrity and redox-inflammatory pathways in type 2 diabetes mellitus: a randomized double-blind placebo-controlled study.
- 2026-04
- RCT
- European journal of nutrition 65(3)
- Drielly Rodrigues Viudes
- Alanna Ramalho Mateus
- Cristina Antoniali Silva
- Maria do Carmo Franco
- PubMed: 41984245
- DOI: 10.1007/s00394-026-03963-3
- High evidence
- Rigorous Journal
- Clinical
CLE significantly reduced markers of endothelial glycocalyx shedding, including HA (259.8 vs. 371.7 ng/mL; P = 0.002)
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 1200 mg/day