Efficacy and safety of Vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: a prospective, open-label study.
- 2014-03
- Clinical Trial
- Advances in therapy 31(3)
- Mikio Momoeda
- Hidetaka Sasaki
- Eiko Tagashira
- Masayuki Ogishima
- Yuichi Takano
- Kazunori Ochiai
- PubMed: 24604699
- DOI: 10.1007/s12325-014-0106-z
- Moderate evidence
- Clinical
Eight patients exhibited non-serious adverse events, one of which was allergic dermatitis whose causal relationship with VAC was not ruled out.
- Effect
- Harmful
- Effect size
- Small
- Dose
- 20 mg/day