The effects of combined calcium and vitamin D supplementation on bone mineral density and fracture risk in postmenopausal women with osteoporosis: a systematic review and meta-analysis of randomized controlled trials.
- 2025-10-08
- Meta-Analysis · n = 869
- BMC musculoskeletal disorders 26(1)
- Bo Cong
- Haiguang Zhang
- PubMed: 41063100
- DOI: 10.1186/s12891-025-09089-7
- High evidence
- Clinical
Subgroup analyses revealed improvements in serum 25‑hydroxyvitamin D levels (25OHD), especially in participants with baseline deficiencies (Z = 10.48, p < 0.001)
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes