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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Calcium and Reduced Bone Loss

Doses used in studies

mg/day: 500 (median 500, IQR 500–500) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

Effect of Low-Dose Vitamin K2 Supplementation on Bone Mineral Density in Middle-Aged and Elderly Chinese: A Randomized Controlled Study.
- 2020-02-14
- RCT · n = 311
- Calcified tissue international 106(5)
- - Yingfeng Zhang
  - Zhipeng Liu
  - Lili Duan
  - Yeyu Ji
  - Sen Yang
  - Yuan Zhang
  - Hongyin Li
  - Yu Wang
  - Peng Wang
  - Jiepeng Chen
  - Ying Li
- PubMed: 32060566
- DOI: 10.1007/s00223-020-00669-4
1 Insight on
- Reduced Bone Loss
- High evidence
- Large Human Trial
- Clinical
in combination with calcium and vitamin D3 brought no additional effects
Effect
Neutral
Effect size
Small
Significant
No
Dose
10 µg/day