Calcium and Reduced Energy Intake

• Dose-related Effects of Calcium to Enhance the Effects of L-tryptophan on Gut Hormones and Energy Intake in Obesity.

  • 2025-08-01
  • RCT
  • The Journal of clinical endocrinology and metabolism 110(9)
  • • Javad Anjom-Shoae
    • Penelope C E Fitzgerald
    • Michael Horowitz
    • Jens J Holst
    • Jens F Rehfeld
    • Simon Veedfald
    • Christine Feinle-Bisset

  • PubMed: 39785828
  • DOI: 10.1210/clinem/dgaf008

  1 Insight on

  • Reduced Energy Intake

  • High evidence
  • Clinical

  Calcium, in a dose of 1000 mg, stimulated GLP-1, PYY, and pyloric pressures alone (all P < .05) and enhanced the effects of Trp to stimulate CCK, GLP-1, and PYY (all P < .05), associated with greater suppression of energy intake (P = .01).

  Effect

  Beneficial

  Effect size

  Moderate

  Dose

  500 mg

• Calcium-Sensing Receptor Regulation of Gastrointestinal Hormone Secretion.

  • 2025-12-01
  • Review
  • Endocrine reviews 47(2)
  • • Javad Anjom-Shoae
    • Simon Veedfald
    • Arthur D Conigrave
    • Michael Horowitz
    • Christine Feinle-Bisset

  • PubMed: 41321115
  • DOI: 10.1210/endrev/bnaf040

  3 Insights on

  • Reduced Energy Intake

  • Low evidence

  associated with reductions in both energy intake

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes