Calcium and Reduced Maternal Death or Severe Morbidity

• Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.

  • 2025-12-03
  • Meta-Analysis · n = 9,430
  • The Cochrane database of systematic reviews 2026(1)
  • • Catherine A Cluver
    • Christa Rohwer
    • Anke C Rohwer

  • PubMed: 41330480
  • DOI: 10.1002/14651858.cd001059.pub6

  8 Insights on

  • Reduced Maternal Death or Severe Morbidity

  • High evidence
  • Pregnant Women

  Calcium probably results in little to no difference in the composite outcome maternal death or severe morbidity (RR 0.80, 95% CI 0.54 to 1.19; 1 RCT, 8312 women; moderate-certainty evidence).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  No

  Dose

  varied across trials