Iodine and Improved Neurodevelopmental Performance

Doses used in studies

µg/day: 150–300 (median 225, IQR 150–300) — 1 study

Safety in these studies

adverse neurodevelopmental outcomesIncreased riskOR = 1.19, 95% CI: 1.03 to 1.39
Binary outcome analysis confirmed increased odds of adverse neurodevelopmental outcomes (OR = 1.19, 95% CI: 1.03 to 1.39, p = 0.026).
from: Maternal Iodine Status During Pregnancy and Child Neurodevelopment: A Systematic Review an

1 of 1 paper

Maternal Iodine Status During Pregnancy and Child Neurodevelopment: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.

2026-05-05
Meta-Analysis
Nutrients 18(9)
- Qingshan Luo
- Zhou Wang
- Jie Jiang
- Xianru Luo
- Tingxuan Feng
- Chao Wang
- Shasha Ruan
- Xiaoheng Li

PubMed: 42124075
DOI: 10.3390/nu18091474

5 Insights on

Improved Neurodevelopmental Performance

High evidence
Rigorous Journal
Pregnant Women

the pooled analysis revealed a significant negative association between suboptimal maternal iodine status and child neurodevelopmental performance (Hedges' g = -0.13, 95% CI: -0.20 to -0.06, p < 0.001)

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: dietary iodine intake (approximately 150–300 µg/d)