adverse effectsIncreased riskRR 1.29 (95% CI 0.83 to 2.02)
The evidence is very uncertain for adverse effects (21.6% versus 18.0%; RR 1.29, 95% CI 0.83 to 2.02; 12 trials, 2423 women; very low-certainty evidence)
from: Daily oral iron supplementation during pregnancy.severe anaemiaIncreased riskSerious adverse eventRR 0.22 (95% CI 0.01 to 3.20)
The evidence is very uncertain for ... severe anaemia (Hb < 70 g/L) in the second/third trimester (< 1% versus 3.6%; RR 0.22, 95% CI 0.01 to 3.20; 8 trials, 1398 women; very low-certainty evidence)
from: Daily oral iron supplementation during pregnancy.congenital anomaliesNo significant differenceSerious adverse eventRR 0.88 (95% CI 0.58 to 1.33)
There may be little to no difference in ... congenital anomalies, including neural tube defects (41 versus 48 events; RR 0.88, 95% CI 0.58 to 1.33; 4 trials, 14,377 infants; low-certainty evidence)
from: Daily oral iron supplementation during pregnancy.maternal deathNo significant differenceSerious adverse eventRR 0.57 (95% CI 0.12 to 2.69)
There is probably little to no difference in maternal death (2 versus 4 events, RR 0.57, 95% CI 0.12 to 2.69; 3 trials, 14,060 women; moderate-certainty evidence)
from: Daily oral iron supplementation during pregnancy.neonatal deathNo significant differenceSerious adverse eventRR 0.98 (95% CI 0.77 to 1.24)
There may be little to no difference in neonatal death (1.4% versus 1.5%, RR 0.98, 95% CI 0.77 to 1.24; 4 trials, 17,243 infants; low-certainty evidence)
from: Daily oral iron supplementation during pregnancy.clinical malariaReported
No trials reported clinical malaria or infection during pregnancy.
from: Daily oral iron supplementation during pregnancy.