Iron and Reduced First Heart Failure Hospitalization or Cardiovascular Death

• Intravenous iron therapy for patients with heart failure: a meta-analysis stratified by chronic kidney disease status.

  • 2026-03-27
  • Meta-Analysis · n = 7,009
  • BMC cardiovascular disorders 26(1)
  • • Yiran Du
    • Yingnan Liang
    • Jie Lv
    • Zhen Wang
    • Xiaowen Li
    • Zhenjie Chen
    • Jingwei Zhou

  • PubMed: 41896739
  • DOI: 10.1186/s12872-026-05672-5

  3 Insights on

  • Reduced First Heart Failure Hospitalization or Cardiovascular Death

  • High evidence
  • Clinical

  IV iron therapy showed a significantly reduced incidence of first heart failure hospitalization or cardiovascular death (RR = 0.79, 95% CI: 0.72–0.86, P < 0.001)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes