Iron and Reduced Length of Hospital Stay

• Comparative Efficacy of Perioperative Blood Conservation Agents in Pediatric Cranial Vault Remodeling: A Systematic Review and Network Meta-Analysis.

  • 2025-10-15
  • Meta-Analysis · n = 1,072
  • Neurosurgery 98(3)
  • • Christopher C Padilla
    • Michael Farid
    • Parker Smith
    • Kwadwo Darko
    • Kwadwo Darko
    • Sean O'Leary
    • Bennett Levy
    • Umaru Barrie
    • Hammad Khan
    • Salah G Aoun
    • David H Harter

  • PubMed: 41090904
  • DOI: 10.1227/neu.0000000000003798

  4 Insights on

  • Reduced Length of Hospital Stay

  • High evidence
  • Clinical

  Combination of TXA + EPO + iron was associated with significantly reduced hospital length of stay (standard mean difference: -1.00, 95% CI: -1.71 to -0.29).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes