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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Magnesium and Increased Narcotic Consumption

Doses used in studies

mg/day: 250 (median 250, IQR 250–250) — 1 study

Time to effect

Median: 10 days · IQR 10 days–10 days · Range 10 days–10 days — Reported in 1 of 1 study

1 of 1 paper

Comparison of oral ketorolac and oral magnesium for postoperative pain management in anorectal surgery: A randomized double-blind clinical trial.
- 2026-01
- RCT · n = 104
- The Journal of international medical research 54(1)
- - Seyed Jalal Eshagh Hoseini
  - Farzaneh Sadat Ghazi
  - Mohsen Eshraghi
  - Mostafa Vahedian
  - Mohammad Reza Pashaei
  - Mojdeh Bahadorzadeh
  - Sajjad Ahmadpour
- PubMed: 41529918
- DOI: 10.1177/03000605251409937
2 Insights on
- Increased Narcotic Consumption
- High evidence
- Large Human Trial
- Clinical
Narcotic consumption was higher in the magnesium group than in the ketorolac group (p < 0.001).
Effect
Harmful
Effect size
Moderate
Significant
Yes
Dose
250 mg daily