Magnesium and Reduced Cramp Frequency

• The Role of Electrolytes in Muscle Pain Syndromes: A Systematic Review and Meta-Analysis With Implications for Temporomandibular Disorder.

  • 2026-06
  • Meta-Analysis
  • International dental journal 76(3)
  • • Shankargouda Patil
    • Andrea Falkowski
    • Venkata Suresh Venkataiah
    • Shilpa Bhandi
    • Frank W Licari
    • Amey G Patil

  • PubMed: 41812583
  • DOI: 10.1016/j.identj.2026.109488

  2 Insights on

  • Reduced Cramp Frequency

  • High evidence

  In nocturnal or persistent leg cramps in adults (4 trials, N≈396), no significant effect was found (MD -0.42 cramps/week, 95% CI: -1.15 to 0.31, P = .26).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No