Effects of Selenium Supplementation in Patients with Mild Cognitive Impairment or Alzheimer's Disease: A Systematic Review and Meta-Analysis.
- 2022-08-05
- Meta-Analysis · n = 1,350
- Nutrients 14(15)
- Meire Ellen Pereira
- Júlia Vicentin Souza
- Maria Eduarda Andrade Galiciolli
- Fernanda Sare
- Giovanna Scorsin Vieira
- Isabeli Lopes Kruk
- Cláudia Sirlene Oliveira
- PubMed: 35956381
- DOI: 10.3390/nu14153205
- High evidence
- Rigorous Journal
- Clinical
Studies that evaluated only Se supplementation observed an improvement in Se levels, glutathione peroxidase (GPX) activity, and in some cognitive tests in MCI patients
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes