Selenium and Reduced Clinical Activity Index

• Efficacy and safety of dietary supplements for the treatment of ulcerative colitis, a network meta-analysis.

  • 2026-04-22
  • Systematic Review · n = 491
  • Frontiers in medicine 13
  • • Rong Xu
    • Zhiyu Zhang
    • Ying Li
    • Zhijiu Wu

  • PubMed: 42100281
  • DOI: 10.3389/fmed.2026.1816535

  3 Insights on

  • Reduced Clinical Activity Index

  • High evidence
  • Clinical

  selenium [MD = -2.43, 95% CI (-4.85 to -0.01)] had significant advantages compared with conventional medical treatment or placebo in reducing clinical activity index.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes