Shilajit and Improved Endothelial Cell Migration

Doses used in studies

mg/day: 250 (median 250, IQR 250–250) — 1 study

Time to effect

Median: 3.3 months · IQR 3.3 months–3.3 months · Range 3.3 months–3.3 months — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
Supplementation with shilajit for 14 weeks was not associated with any reported adverse effect within this period.
from: Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit S

1 of 1 paper

Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix Mechanisms.

2019-06-04
RCT
Journal of the American College of Nutrition 38(6)
- Amitava Das
- Mohamed S El Masry
- Surya C Gnyawali
- Surya C Gnyawali
- Subhadip Ghatak
- Kanhaiya Singh
- Richard Stewart
- Madeline Lewis
- Abhijoy Saha
- Gayle Gordillo
- Savita Khanna

PubMed: 31161927
DOI: 10.1080/07315724.2018.1564088

3 Insights on

Improved Endothelial Cell Migration

High evidence
Rigorous Journal
Adults

Pathway analysis identified shilajit-inducible genes relevant to endothelial cell migration, growth of blood vessels, and ECM which were validated by quantitative real-time polymerase chain reaction (RT-PCR) analysis.

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: 250 mg bid