Shilajit and Increased Type 1 Collagen Synthesis

Doses used in studies

mg/day: 1,000 (median 1,000, IQR 1,000–1,000) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

Effects of 8 Weeks of Shilajit Supplementation on Serum Pro-c1α1, a Biomarker of Type 1 Collagen Synthesis: A Randomized Control Trial.

2022-12-22
RCT
Journal of dietary supplements 21(1)
- Tyler J Neltner
- Prakash K Sahoo
- Robert W Smith
- John Paul V Anders
- Jocelyn E Arnett
- Richard J Schmidt
- Glen O Johnson
- Sathish Kumar Natarajan
- Terry J Housh

PubMed: 36546868
DOI: 10.1080/19390211.2022.2157522

2 Insights on

Increased Type 1 Collagen Synthesis

High evidence
Adults

There were significant (Low dose: p = 0.008, d = 1.2; High dose: p = 0.007, d = 1.3) increases in serum pro-c1α1 from pre- (Low dose: 42.5 ± 12.4 ng·mL-1; High dose: 42.7 ± 12.7 ng·mL-1) to post-supplementation (Low dose: 82.3 ± 46.5 ng·mL-1; High dose: 113.1 ± 78.7 ng·mL-1) for the low and high dose groups

Effect: Beneficial
Effect size: Large
Significant: Yes
Dose: 1000 mg/day