Zinc and Reduced Cervicovaginal Iron Concentration

• Cervicovaginal lavage fluid iron and manganese levels in women with and without vaginitis.

  • 2026-02-24
  • RCT · n = 80
  • BMC women's health 26(1)
  • • Barbara Kozma
    • David Ratonyi
    • Bence Kozma
    • Peter Takacs
    • Attila G Sipos

  • PubMed: 41731507
  • DOI: 10.1186/s12905-026-04339-9

  2 Insights on

  • Reduced Cervicovaginal Iron Concentration

  • High evidence
  • Clinical

  In subgroup analyses, Fe remained significantly higher in vaginitis compared with controls among women who did not use the hydrogel (60.69±26.53 vs. 47.27±21.87; p=0.041), whereas the difference was attenuated and no longer significant among hydrogel users (53.64±23.62 vs. 41.75±17.71; p=0.148).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  intravaginal zinc-containing hydrogel