Zinc and Reduced Viral Load

Doses used in studies

mg/day: 100 (median 100, IQR 100–100) — 1 study

Time to effect

Median: 7 days · IQR 7 days–7 days · Range 7 days–7 days — Reported in 1 of 2 studies

Safety in these studies

Overall tolerabilityReported
We did not observe any changes in the Siddha-based clinical examination and adverse events in both groups.
from: Kabasura Kudineer (KSK), a poly-herbal Siddha medicine, reduced SARS-CoV-2 viral load in a

2 of 2 papers

Effect of Micronutrients on HIV-Related Clinical Outcomes Among Adults Living With HIV on Antiretroviral Therapy: Systematic Review and Meta-analysis.
- 2024-11-22
- Meta-Analysis · n = 4,000
- Nutrition reviews 83(7)
- - Elile Monisola Okoka
  - Moshood Abiodun Kuyebi
  - Oluwafemi Temitayo Oyadiran
  - Temitayo Rebecca Okusanya
  - Emmanuella Onaku
  - Moshood Olanrewaju Omotayo
  - Ajibola Ibraheem Abioye
- PubMed: 39576658
- DOI: 10.1093/nutrit/nuae171
7 Insights on
- Reduced Viral Load
- High evidence
- Clinical
Moderate- or high-certainty evidence indicates that there is probably no effect of zinc supplementation on log10 viral load
Effect
Neutral
Effect size
Small
Significant
No
Kabasura Kudineer (KSK), a poly-herbal Siddha medicine, reduced SARS-CoV-2 viral load in asymptomatic COVID-19 individuals as compared to vitamin C and zinc supplementation: findings from a prospective, exploratory, open-labeled, comparative, randomized controlled trial, Tamil Nadu, India.
- 2021-09-15
- RCT
- Trials 22(1)
- - S Natarajan
  - C Anbarasi
  - P Sathiyarajeswaran
  - P Manickam
  - S Geetha
  - R Kathiravan
  - P Prathiba
  - M Pitchiahkumar
  - P Parthiban
  - K Kanakavalli
  - P Balaji
- PubMed: 34526104
- DOI: 10.1186/s13063-021-05583-0
7 Insights on
- Reduced Viral Load
- High evidence
- Clinical
Viral load in terms of the CT value ... declined significantly on the seventh day in the KSK group and that of the control group, more pronounced in the study group.
Effect
Neutral
Effect size
Small
Significant
No
Dose
100 mg evening daily for 7 days

Zinc and Reduced Viral Load

Effect of Micronutrients on HIV-Related Clinical Outcomes Among Adults Living With HIV on Antiretroviral Therapy: Systematic Review and Meta-analysis.

Kabasura Kudineer (KSK), a poly-herbal Siddha medicine, reduced SARS-CoV-2 viral load in asymptomatic COVID-19 individuals as compared to vitamin C and zinc supplementation: findings from a prospective, exploratory, open-labeled, comparative, randomized controlled trial, Tamil Nadu, India.