Zinc and Reduced VVC Recurrence

• Zinc-based therapies for prevention and treatment of vulvovaginal candidiasis: a systematic review and meta-analysis.

  • 2026-05-12
  • Meta-Analysis · n = 192
  • BMC infectious diseases 26(1)
  • • Jonani Bwambale
    • Betty Nakawuka
    • Gerald Mboowa
    • Felix Bongomin
    • Richard Kwizera

  • PubMed: 42121064
  • DOI: 10.1186/s12879-026-13520-2

  4 Insights on

  • Reduced VVC Recurrence

  • High evidence
  • Clinical

  One RCT (n=68) showed that zinc supplementation produced a numerically lower 90-day reinfection rate that did not reach statistical significance (28.6% vs. 48.5%, RR=0.59, 95% CI: 0.31-1.11, p=0.134).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No