Anaerobutyricum hallii and Increased Endogenous Acrolein Formation

• Microbial Transformation of Dietary Glycerol Contributes to Intestinal Acrolein Formation and Urinary Excretion.

  • 2025-10-29
  • Observational · n = 20
  • Molecular nutrition & food research 69(24)
  • • Clarissa Schwab
    • Hanna Lang
    • Simone Stegmüller
    • Jiri Hosek
    • Angeliki Marietou
    • Lucia Huertas-Díaz
    • Qing Li
    • Asta Petrine Smedgaard Krings
    • Andrea Zander
    • Ulrik Kræmer Sundekilde
    • Elke Richling

  • PubMed: 41159664
  • DOI: 10.1002/mnfr.70289

  2 Insights on

  • Increased Endogenous Acrolein Formation

  • Moderate evidence
  • Rigorous Journal

  Our data show that oral fat/glycerol intake together with intestinal microbiota activity might temporarily increase endogenous acrolein formation and that urinary biomarkers link to the intestinal microbiome.

  Effect

  Harmful

  Effect size

  Small