Anaerobutyricum hallii and Increased Urinary Acrolein Biomarkers

• Microbial Transformation of Dietary Glycerol Contributes to Intestinal Acrolein Formation and Urinary Excretion.

  • 2025-10-29
  • Observational · n = 20
  • Molecular nutrition & food research 69(24)
  • • Clarissa Schwab
    • Hanna Lang
    • Simone Stegmüller
    • Jiri Hosek
    • Angeliki Marietou
    • Lucia Huertas-Díaz
    • Qing Li
    • Asta Petrine Smedgaard Krings
    • Andrea Zander
    • Ulrik Kræmer Sundekilde
    • Elke Richling

  • PubMed: 41159664
  • DOI: 10.1002/mnfr.70289

  2 Insights on

  • Increased Urinary Acrolein Biomarkers

  • Moderate evidence
  • Rigorous Journal

  Levels of urine biomarkers N-acetyl-S-(3-hydroxypropyl)-L-cysteine (3-HPMA) and N-acetyl-S-(carboxyethyl)-L-cysteine (CEMA) were higher after the consumption of meals with high glycerol levels, suggesting immediate microbial transformation to acrolein.

  Effect

  Harmful

  Effect size

  Small