Bacillus clausii SC-109 and Reduced Duration of Acute Diarrhoea

• Probiotics for treating acute infectious diarrhoea.

  • 2020-12-08
  • Meta-Analysis · n = 4,056
  • The Cochrane database of systematic reviews 2020(12)
  • • Shelui Collinson
    • Andrew Deans
    • April Padua-Zamora
    • Germana V Gregorio
    • Chao Li
    • Leonila F Dans
    • Stephen J Allen

  • PubMed: 33295643
  • DOI: 10.1002/14651858.cd003048.pub4

  1 Insight on

  • Reduced Duration of Acute Diarrhoea

  • High evidence

  In six trials (433 participants) of Lactobacillus reuteri, there was consistency amongst findings (I² = 0%), but risk of bias was present in all included studies... Probiotics probably make little or no difference to the number of people who have diarrhoea lasting 48 hours or longer, and we are uncertain whether probiotics reduce the duration of diarrhoea.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No