Bacillus clausii and Improved Stool Consistency

• Efficacy of Bacillus clausii in Pediatric Functional Constipation: A Pilot of a Randomized, Double-Blind, Placebo-Controlled Trial.

  • 2023-02-09
  • RCT · n = 38
  • Indian pediatrics 60(6)
  • • Ponlakit Lojanatorn
    • Jirachart Phrommas
    • Pornthep Tanpowpong
    • Songpon Getsuwan
    • Chatmanee Lertudomphonwanit
    • Suporn Treepongkaruna

  • PubMed: 36757002
  • DOI: 10.1007/s13312-023-2907-0

  5 Insights on

  • Improved Stool Consistency

  • High evidence
  • Children

  On within-group analyses, the mean (SD) of Bristol stool grade increased in both the B. clausii [1.7 (0.5) to 2.8 (1.2); P=0.003] and placebo [1.8 (0.5) to 2.8 (1.2); P=0.01] groups.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  once daily for four weeks