Bacillus coagulans GBI-30, 6086 and Improved Gastrointestinal Function

• Impact of Heyndrickxia (Bacillus) coagulans GBI-30, 6086 (BC30) probiotic on gastrointestinal function in healthy adults: a randomised controlled trial.

  • 2025-07-22
  • RCT · n = 111
  • Beneficial microbes 17(1)
  • • H Gang
    • J Wei
    • L V McFarland
    • R Zahra
    • M E Saez
    • R Blanco-Rojo
    • M Millette

  • PubMed: 40707016
  • DOI: 10.1163/18762891-bja00084

  1 Insight on

  • Improved Gastrointestinal Function

  • High evidence
  • Large Human Trial
  • Rigorous Journal

  Functional GI symptoms improved significantly in adults given BC30 compared to placebo: increase in number of stools/week ( P = 0.036), improved fecal consistency ( P < 0.001) and fewer participants had constipation ( P < 0.001).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes