Bacillus coagulans MTCC 5856 for the management of major depression with irritable bowel syndrome: a randomised, double-blind, placebo controlled, multi-centre, pilot clinical study
- 2018-07-04
- RCT · n = 40
- Food & Nutrition Research 62(0)
- M. Majeed
- K. Nagabhushanam
- S. Arumugam
- Shaheen Majeed
- Furqan Ali
- PubMed: 29997457
- DOI: 10.29219/fnr.v62.1218
- High evidence
- Highly Cited
- Rigorous Journal
Secondary efficacy measures i.e. ... Gastrointestinal Discomfort Questionnaire (GI-DQ) ... also showed significant results (p = 0.01) in B. coagulans MTCC 5856 group compared to placebo group
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 2 × 10^9 cfu (2 billion spores) daily