Bacillus coagulans and Reduced Irritable Bowel Syndrome Symptom Severity Score

Doses used in studies

With Inulin · spores/day: 1 billion (median 1 billion, IQR 1 billion–1 billion) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

Is Bacillus coagulans supplementation plus low FODMAP diet superior to low FODMAP diet in irritable bowel syndrome management?

2019-07-20
RCT
European journal of nutrition 59(5)
- Khadijeh Abhari
- Saeede Saadati
- Fatemeh Hosseini-Oskouiee
- Zahra Yari
- Hedayat Hosseini
- Golbon Sohrab
- Ehsan Hejazi
- Shahram Agah
- Amir Sadeghi
- Azita Hekmatdoost

PubMed: 31327047
DOI: 10.1007/s00394-019-02060-y

7 Insights on

Reduced Irritable Bowel Syndrome Symptom Severity Score

High evidence
Rigorous Journal
Clinical

only improvement in severity score was significantly higher in probiotic group compared with placebo group (P = 0.001). Moreover, the frequency of patients with clinical improvement in IBS-symptom severity scale (IBS-SSS) was significantly more in probiotic group compared to placebo group (P = 0.038).

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 10^9 spores/day plus 400 mg inulin