Bacillus subtilis HU58 and Reduced Duration of Antibiotic-Associated Diarrhea

• Effects of spore-forming probiotic Bacillus subtilis HU58™ in children with antibiotic-associated diarrhoea: a randomised, double-blind, placebo-controlled trial.

  • 2025-07-25
  • RCT · n = 68
  • Beneficial microbes 17(1)
  • • K Sorensen
    • P Jog
    • S Mankar
    • C Holz
    • S Jadhav

  • PubMed: 40716758
  • DOI: 10.1163/18762891-bja00086

  3 Insights on

  • Reduced Duration of Antibiotic-Associated Diarrhea

  • High evidence
  • Rigorous Journal

  By day 3, 93.5% of the probiotic group had normal BSS types, versus 22.6% in the placebo group ( P < 0.001). Almost all subjects in both groups had normal stool types by day 7.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes