Bacillus subtilis SNZ-1972 and Reduced Susceptibility to Bacterial Infection

• Mechanism for nonspecific immunity of Listeria monocytogenes in rats mediated by platelets and the clotting system.

  • 1981-08
  • Infection and immunity 33(2)
  • • W A Davies
    • V P Ackerman
    • D S Nelson

  • PubMed: 6792078
  • DOI: 10.1128/iai.33.2.477-481.1981

  1 Insight on

  • Reduced Susceptibility to Bacterial Infection

  • Low evidence
  • Animal Study

  The susceptibility of rats to Listeria infection was enhanced by anticoagulant treatment. Rats were infected with Listeria organisms with and without administration of heparin. Heparin-treated rats developed bacteremia, and some died. None of the control rats developed bacteremia or died.

  Effect

  Beneficial

  Effect size

  Large