Bifidobacterium adolescentis and Improved Gut-Brain Axis Function

• Dietary patterns influence the in silico GABA production capacity of Bifidobacterium adolescentis HD17T2H and other human gut bacteria.

  • 2026-03-11
  • Scientific reports 16(1)
  • • Ann Homscheid
    • Karlis Arturs Moors
    • Bram Nap
    • Wolfgang Lieb
    • Andre Franke
    • Matthias Laudes
    • Ines Thiele
    • Christoph Kaleta
    • Georgios Marinos

  • PubMed: 41813835
  • DOI: 10.1038/s41598-026-43006-9

  1 Insight on

  • Improved Gut-Brain Axis Function

  • Low evidence
  • Rigorous Journal

  Gamma-aminobutyric acid (GABA) is a neurotransmitter that inhibits neuronal excitability and also affects mucosal function and gut motility... our modelling approach highlights that nutrient availability is a central determinant of bacterial GABA production.

  Effect

  Beneficial

  Effect size

  Small