Bifidobacterium treatment for chronic low back pain in patients with Modic changes: study protocol for a multicenter, randomized, placebo-controlled trial.
- 2025-09-24
- RCT
- Trials 26(1)
- Sunqi Nian
- Chengjin Li
- Na Li
- Fei Chen
- Caiwang Zhao
- Guangyao Zhang
- Sheng Lu
- Jiayu Chen
- PubMed: 40993700
- DOI: 10.1186/s13063-025-09084-2
- High evidence
- Clinical
The primary outcome will be the change in the Simplified Chinese Roland-Morris Disability Questionnaire (SCRMDQ) score at 3, 6, and 12 months post-treatment.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- twice daily for three months (dose not specified in abstract)