Orally Ingested Probiotics, Prebiotics, and Synbiotics as Countermeasures for Respiratory Tract Infections in Nonelderly Adults: A Systematic Review and Meta-Analysis.
- 2022-11
- Meta-Analysis · n = 9,179
- Advances in nutrition (Bethesda, Md.) 13(6)
- Julie L Coleman
- Adrienne Hatch-McChesney
- Stephanie D Small
- Jillian T Allen
- Elaine Sullo
- Richard T Agans
- Heather S Fagnant
- Asma S Bukhari
- J Philip Karl
- PubMed: 35948276
- DOI: 10.1093/advances/nmac086
- High evidence
Probiotics reduced the risk of experiencing ≥1 RTI (relative risk = 0.91; 95% CI: 0.84, 0.98; P = 0.01), and total days (rate ratio = 0.77; 95% CI: 0.71, 0.83; P < 0.001), duration (Hedges' g = -0.23; 95% CI: -0.39, -0.08; P = 0.004), and severity (Hedges' g = -0.16; 95% CI: -0.29, -0.03; P = 0.02) of RTIs.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes