Effect of Probiotic Supplementation on Intestinal Permeability in Overweight and Obesity: A Systematic Review of Randomized Controlled Trials and Animal Studies.
- 2024-01
- Systematic Review · n = 13
- Advances in nutrition (Bethesda, Md.) 15(1)
- Zachary DiMattia
- Janhavi J Damani
- Emily Van Syoc
- Connie J Rogers
- PubMed: 38072119
- DOI: 10.1016/j.advnut.2023.100162
- High evidence
Eleven of 12 animal studies reported a positive effect of probiotic supplementation in reducing intestinal permeability. However, results from clinical trials were inconsistent, with half reporting reductions in serum LPS and half reporting no differences after probiotic supplementation. Bifidobacterium, Lactobacillus, and Akkermansia emerged as the most common genera in probiotic formulations among the animal and clinical studies that yielded positive results
- Effect
- Beneficial
- Effect size
- Moderate