Bifidobacterium animalis subsp. lactis BB-12 and Increased Abundance of Bifidobacterium animalis

• Matrix Effects on the Delivery Efficacy of Bifidobacterium animalis subsp. lactis BB-12 on Fecal Microbiota, Gut Transit Time, and Short-Chain Fatty Acids in Healthy Young Adults.

  • 2021-08-25
  • RCT · n = 36
  • mSphere 6(4)
  • • Zhaoyong Ba
    • Yujin Lee
    • Huicui Meng
    • Penny M Kris-Etherton
    • Connie J Rogers
    • Zachery T Lewis
    • David A Mills
    • Emily J Furumoto
    • M Laura Rolon
    • Jennifer A Fleming
    • Robert F Roberts

  • PubMed: 34232082
  • DOI: 10.1128/msphere.00084-21

  5 Insights on

  • Increased Abundance of Bifidobacterium animalis

  • High evidence

  "Bifidobacterium-specific terminal restriction fragment length polymorphism analysis revealed a significantly higher percentage of B. animalis after consuming PRE and POST compared to baseline, YS, CAP, and final washout"

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  log10 10 ± 0.5 CFU/day

• Effects of supplementation with Bifidobacterium animalis subsp. lactis CECT 8145-in live probiotic and heat-treated postbiotic form-on fecal metabolites, fecal microbiota, blood metabolites and systemic biomarkers of oxidative stress and inflammation, and white blood cell gene expression of adult cats.

  • 2025-11-29
  • RCT · n = 90
  • Journal of animal science 103
  • • Sergio Miranda de Souza Junior
    • Empar Chenoll
    • Adrian Howard-Varona
    • Araceli Lamelas
    • Juan F Martinez-Blanch
    • Gary M Davenport
    • Sophie Nixon
    • Fei He
    • Maria R C de Godoy

  • PubMed: 41117771
  • DOI: 10.1093/jas/skaf355

  5 Insights on

  • Increased Abundance of Bifidobacterium animalis

  • Low evidence
  • Animal Study

  At a species level, cats in the PRO group had an increased abundance of Bifidobacterium animalis over time (P < 0.05).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes